№ 4Hematology17 min read
Immune-hemolytic anemias
1. Big picture
Immune-hemolytic anemias are hemolytic anemias caused by antibodies and/or complement directed against red blood cells.
The exam pattern is:
anemia + jaundice + high reticulocytes + high lactate dehydrogenase + indirect bilirubin ↑ + haptoglobin ↓ + positive direct Coombs test → immune hemolysis.
The most important clinical split is:
| Type | Antibody | Temperature | Main site of hemolysis |
|---|---|---|---|
| **Warm autoimmune hemolytic a |
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