Staphylococcal and streptococcal infections
1. Big picture
Staphylococci and streptococci are Gram-positive cocci and among the most important causes of community-acquired and hospital-acquired bacterial infections.
For the exam, separate them first by microscopy and basic tests:
| Feature | Staphylococci | Streptococci |
|---|---|---|
| Microscopy | Gram-positive cocci in clusters | Gram-positive cocci in chains/pairs |
| Catalase | Positive | Negative |
| Main dangerous species | Staphylococcus aureus | Streptococcus pyogenes, S. pneumoniae |
| Typical pattern | Abscesses, catheter infection, bacteremia, endocarditis | Pharyngitis, erysipelas/cellulitis, pneumonia, meningitis, postinfectious immune disease |
The practical clinical rule:
Staphylococcus aureus makes pus, abscesses, bacteremia, and metastatic infection. Streptococcus pyogenes spreads rapidly through tissue and causes toxin-mediated shock. Streptococcus pneumoniae causes pneumonia, meningitis, bacteremia, and severe infection in asplenia.
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