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8Toxicology12 min read

Corrosive poisoning (acids, bases)

1. Big picture

Corrosive poisoning means chemical burn injury caused by ingestion or contact with a strong acid or alkali/base. In Internal Medicine toxicology, the examiner mainly wants four things:

  1. Recognize airway and perforation danger early.
  2. Know that oral burns do not reliably predict esophageal/gastric injury.
  3. Do not “neutralize,” induce vomiting, lavage, or blindly insert a nasogastric tube.
  4. Use early endoscopy/CT to grade injury and guide management.

The main life-threatening problems are laryngeal edema/asphyxia, esophageal or gastric perforation, mediastinitis, peritonitis, shock, bleeding, and later strictures.


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