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14Neurology13 min read

Topic 14. Gaze disturbances and their localizing significances

1. Big picture

A gaze disturbance means a problem of conjugate eye movement: both eyes are supposed to move together in the same direction, but the patient cannot direct both eyes normally to one side or vertically.

This topic is highly localizing. In the exam, the key is to distinguish:

ProblemEye movement patternDiplopia?Main localization
Gaze disturbanceBoth eyes fail to move together in one directionUsually no diplopiaSupranuclear/cortical or brainstem gaze centers
Ocular motor palsyOne eye does not move properly → eyes become disconjugateUsually diplopiaIII, IV, VI nucleus/nerve, neu

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