Thyroid cancer
1. Big picture
Thyroid cancer is a malignant tumor arising from thyroid follicular cells or parafollicular C cells. Surgically, the key issue is not simply “remove the thyroid,” but to decide:
- Is the nodule malignant or suspicious?
- What histological type is likely?
- Is disease confined to thyroid, or are lymph nodes/distant metastases present?
- Is lobectomy enough, or is total thyroidectomy needed?
- Does the patient need central/lateral neck dissection?
- Does the patient need radioactive iodine, thyroid-stimulating hormone suppression, calcitonin follow-up, or palliative airway management?
Most thyroid cancers are differentiated thyroid cancers, especially papillary and follicular carcinoma, which usually have good prognosis. Medullary and anaplastic carcinoma are much more exam-important because they change the management logic.
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