№ 4Endocrinology14 min read
Diabetes insipidus, syndrome of inappropriate ADH secretion (SIADH)
Big picture
This topic is about water balance disorders caused by abnormal antidiuretic hormone (ADH/arginine vasopressin) action.
There are two opposite clinical pictures:
| Disorder | ADH problem | Main water problem | Serum sodium tendency | Urine |
|---|---|---|---|---|
| Diabetes insipidus (DI) | Too little ADH effect | Water loss | Hypernatremia if patient cannot drink | Large volume, dilute urine |
| SIADH | Too much ADH effect |
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