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18Hematology18 min read

Thrombocytopenias and other platelet disorders

1. Big picture

Platelet disorders cause primary hemostasis failure, so the bleeding pattern is typically:

Petechiae + purpura + mucosal bleeding + epistaxis + gum bleeding + menorrhagia + immediate bleeding after procedures.

This is different from coagulation factor deficiency, which causes:

Deep muscle hematomas + hemarthroses + delayed post-operative bleeding.

The examiner wants you to separate two big groups:

ProblemPlatelet countPlatelet functionTypical examples

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