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№ 17Hematology16 min read

Haemopoietic stem cell transplantation (types, indications, complications)

1. Big picture

Haemopoietic stem cell transplantation (HSCT) means giving haematopoietic stem cells to restore bone marrow function after myeloablative or immunosuppressive treatment, or to replace a diseased marrow/immune system.

The oral exam core:

Autologous HSCT = patient’s own stem cells → high-dose chemotherapy rescue.
Allogeneic HSCT = donor stem cells → new immune system + graft-versus-leukemia effect, but risk of GVHD.

The key distinction is:

| Type | Main purpose | Main advantage | Main danger | | -------------- | -------------

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